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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF22
All Species:
23.03
Human Site:
T521
Identified Species:
50.67
UniProt:
Q14807
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14807
NP_015556.1
665
73262
T521
P
L
S
H
R
T
V
T
G
A
K
P
L
K
K
Chimpanzee
Pan troglodytes
XP_510910
679
74714
T521
P
L
S
H
R
T
V
T
G
A
K
P
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001104365
657
72278
T513
P
L
L
H
R
T
V
T
V
A
K
P
L
K
K
Dog
Lupus familis
XP_547058
651
71817
T507
P
L
A
R
R
T
V
T
V
A
K
P
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3V300
660
73171
T518
P
P
A
S
Y
S
G
T
V
A
K
P
L
K
K
Rat
Rattus norvegicus
Q5I0E8
657
73037
S515
P
S
S
S
C
S
G
S
V
A
K
P
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYL5
650
73149
R509
S
V
S
E
N
T
F
R
A
P
L
R
G
R
N
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
T487
P
L
H
R
K
Q
S
T
A
A
K
P
R
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
T511
Q
L
E
L
Q
E
E
T
T
L
E
I
R
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
V563
K
D
T
N
Y
S
N
V
D
R
I
K
K
E
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPC6
894
98404
F587
S
Q
L
V
Q
L
T
F
E
A
D
Q
M
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.8
90
N.A.
81.3
81
N.A.
N.A.
N.A.
52.3
50.9
N.A.
29.2
N.A.
28.1
N.A.
Protein Similarity:
100
97.5
96.2
93
N.A.
88.7
88.8
N.A.
N.A.
N.A.
69.3
66.1
N.A.
46.1
N.A.
45.7
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
53.3
53.3
N.A.
N.A.
N.A.
13.3
46.6
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
100
86.6
86.6
N.A.
66.6
66.6
N.A.
N.A.
N.A.
26.6
60
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
0
19
73
0
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
0
10
10
0
10
10
0
10
0
10
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
19
0
19
0
0
0
10
0
0
% G
% His:
0
0
10
28
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
64
10
10
64
55
% K
% Leu:
0
55
19
10
0
10
0
0
0
10
10
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
64
10
0
0
0
0
0
0
0
10
0
64
0
0
0
% P
% Gln:
10
10
0
0
19
10
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
0
0
19
37
0
0
10
0
10
0
10
19
19
19
% R
% Ser:
19
10
37
19
0
28
10
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
46
10
64
10
0
0
0
0
0
0
% T
% Val:
0
10
0
10
0
0
37
10
37
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _